The Asia-Pacific Software Engineering Conference (APSEC) has long been established as a leading regional conference that gathers researchers and practitioners from academia, industry, and government to exchange knowledge and best practices in software engineering, and to address emerging challenges and solutions in software engineering innovation. This year’s APSEC be held on December 2-5, 2025 in Macao SAR, China. APSEC 2025 will continue in the tradition of previous editions of this regional conference. As in past APSEC series, the main research track features the most recent and significant innovations in the field of software engineering and all its sub-disciplines. APSEC 2025 also invites submissions of high-quality research papers that describe original and unpublished results on theoretical and empirical software engineering research topics.